Motif2Site
Detect binding sites from motifs and ChIP-seq experiments, and compare binding sites across conditions
Bioconductor version: 3.23 · Package version: 1.16.0
Detect binding sites using motifs IUPAC sequence or bed coordinates and ChIP-seq experiments in bed or bam format. Combine/compare binding sites across experiments, tissues, or conditions. All normalization and differential steps are done using TMM-GLM method. Signal decomposition is done by setting motifs as the centers of the mixture of normal distribution curves.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("Motif2Site") Details
| Maintainer | Peyman Zarrineh <peyman.zarrineh@manchester.ac.uk> |
| Author | Peyman Zarrineh [cre, aut] (ORCID: <https://orcid.org/0000-0003-4820-4101>) |
| License | GPL-2 |
| Bug Reports | https://github.com/fls-bioinformatics-core/Motif2Site/issues |
| Downloads rank | 243 |
| Source branch | RELEASE_3_23 |
| biocViews | ChIPSeq, DifferentialPeakCalling, Epigenetics, SequenceMatching, Sequencing, Software |
Documentation
Download
Dependencies
Depends: R (>= 4.1)
Imports: S4Vectors, stats, utils, methods, grDevices, graphics, BiocGenerics, BSgenome, GenomeInfoDb, MASS, IRanges, GenomicRanges, Biostrings, GenomicAlignments, edgeR, mixtools
Suggests: BiocStyle, rmarkdown, knitr, BSgenome.Hsapiens.UCSC.hg38, BSgenome.Mmusculus.UCSC.mm10, BSgenome.Scerevisiae.UCSC.sacCer3, BSgenome.Ecoli.NCBI.20080805