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LegATo

LegATo: Longitudinal mEtaGenomic Analysis Toolkit

Bioconductor version: 3.23 · Package version: 1.6.0

LegATo is a suite of open-source software tools for longitudinal microbiome analysis. It is extendable to several different study forms with optimal ease-of-use for researchers. Microbiome time-series data presents distinct challenges including complex covariate dependencies and variety of longitudinal study designs. This toolkit will allow researchers to determine which microbial taxa are affected over time by perturbations such as onset of disease or lifestyle choices, and to predict the effects of these perturbations over time, including changes in composition or stability of commensal bacteria.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("LegATo")

Details

MaintainerAubrey Odom <aodom@bu.edu>
AuthorAubrey Odom [aut, cre] (ORCID: <https://orcid.org/0000-0001-7113-7598>), Yilong Zhang [ctb] (Author of NMIT functions), Jared Pincus [csl] (ORCID: <https://orcid.org/0000-0001-6708-5262>, other: Naming consultant of package), Jordan Pincus [art] (Artist of LegATo icon)
LicenseMIT + file LICENSE
URLhttps://wejlab.github.io/LegATo-docs/
Bug Reportshttps://github.com/wejlab/LegATo/issues
Downloads rank100
Source branchRELEASE_3_23
biocViewsExperimentData, MicrobiomeData, ReproducibleResearch, SequencingData

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Dependencies

Depends: R (>= 4.4.0)

Imports: animalcules, data.table, dplyr, ggplot2, magrittr, MultiAssayExperiment, plyr, rlang, S4Vectors, stringr, SummarizedExperiment, tibble, tidyr, tidyselect

Suggests: BiocStyle, broom, broom.mixed, circlize, ComplexHeatmap, emmeans, geepack, ggalluvial, ggeffects, grDevices, knitr, lme4, lmerTest, methods, RColorBrewer, rmarkdown, spelling, TBSignatureProfiler, testthat (>= 3.0.0), TreeSummarizedExperiment, usethis, vegan