JohnsonKinaseData

Kinase PWMs based on data published by Johnson et al. 2023 and Yaron-Barir et al. 2024

Bioconductor version: 3.23 · Package version: 1.8.0

The packages provides position specific weight matrices (PWMs) for 303 human serine/threonine and 93 tyrosine kinases originally published in Johnson et al. 2023 (doi:10.1038/s41586-022-05575-3) and Yaron-Barir et al. 2024 (doi:10.1038/s41586-024-07407-y). The package includes basic functionality to score user provided phosphosites. It also includes pre-computed PWM scores ("background scores") for a large collection of curated human phosphosites which can be used to rank PWM scores relative to the background scores ("percentile rank").

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("JohnsonKinaseData")