HPiP

Host-Pathogen Interaction Prediction

Bioconductor version: 3.23 · Package version: 1.18.0

HPiP (Host-Pathogen Interaction Prediction) uses an ensemble learning algorithm for prediction of host-pathogen protein-protein interactions (HP-PPIs) using structural and physicochemical descriptors computed from amino acid-composition of host and pathogen proteins.The proposed package can effectively address data shortages and data unavailability for HP-PPI network reconstructions. Moreover, establishing computational frameworks in that regard will reveal mechanistic insights into infectious diseases and suggest potential HP-PPI targets, thus narrowing down the range of possible candidates for subsequent wet-lab experimental validations.

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HPiP")