HERON
Hierarchical Epitope pROtein biNding
Bioconductor version: 3.23 · Package version: 1.10.0
HERON is a software package for analyzing peptide binding array data. In addition to identifying significant binding probes, HERON also provides functions for finding epitopes (string of consecutive peptides within a protein). HERON also calculates significance on the probe, epitope, and protein level by employing meta p-value methods. HERON is designed for obtaining calls on the sample level and calculates fractions of hits for different conditions.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("HERON") Details
| Maintainer | Sean McIlwain <sean.mcilwain@wisc.edu> |
| Author | Sean McIlwain [aut, cre] (ORCID: <https://orcid.org/0000-0002-3820-8400>), Irene Ong [aut] (ORCID: <https://orcid.org/0000-0002-9353-6941>) |
| License | GPL (>= 3) |
| URL | https://github.com/Ong-Research/HERON |
| Bug Reports | https://github.com/Ong-Research/HERON/issues |
| Downloads rank | 206 |
| Source branch | RELEASE_3_23 |
| biocViews | Microarray, Software |
Documentation
Download
Dependencies
Depends: R (>= 4.4.0), SummarizedExperiment (>= 1.1.6), GenomicRanges, IRanges, S4Vectors
Imports: matrixStats, stats, data.table, harmonicmeanp, metap, cluster, spdep, Matrix, limma, methods
Suggests: knitr, rmarkdown, testthat (>= 3.0.0)