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HERON

Hierarchical Epitope pROtein biNding

Bioconductor version: 3.23 · Package version: 1.10.0

HERON is a software package for analyzing peptide binding array data. In addition to identifying significant binding probes, HERON also provides functions for finding epitopes (string of consecutive peptides within a protein). HERON also calculates significance on the probe, epitope, and protein level by employing meta p-value methods. HERON is designed for obtaining calls on the sample level and calculates fractions of hits for different conditions.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HERON")

Details

MaintainerSean McIlwain <sean.mcilwain@wisc.edu>
AuthorSean McIlwain [aut, cre] (ORCID: <https://orcid.org/0000-0002-3820-8400>), Irene Ong [aut] (ORCID: <https://orcid.org/0000-0002-9353-6941>)
LicenseGPL (>= 3)
URLhttps://github.com/Ong-Research/HERON
Bug Reportshttps://github.com/Ong-Research/HERON/issues
Downloads rank206
Source branchRELEASE_3_23
biocViewsMicroarray, Software

Documentation

Download

Dependencies

Depends: R (>= 4.4.0), SummarizedExperiment (>= 1.1.6), GenomicRanges, IRanges, S4Vectors

Imports: matrixStats, stats, data.table, harmonicmeanp, metap, cluster, spdep, Matrix, limma, methods

Suggests: knitr, rmarkdown, testthat (>= 3.0.0)