GeoDiff
Count model based differential expression and normalization on GeoMx RNA data
Bioconductor version: 3.23 · Package version: 1.18.0
A series of statistical models using count generating distributions for background modelling, feature and sample QC, normalization and differential expression analysis on GeoMx RNA data. The application of these methods are demonstrated by example data analysis vignette.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("GeoDiff") Details
| Maintainer | Maddy Griswold <mgriswold@nanostring.com> |
| Author | Maddy Griswold [cre], Lei Yang [aut], Zhi Yang [aut] |
| License | MIT + file LICENSE |
| URL | https://github.com/Nanostring-Biostats/GeoDiff |
| Bug Reports | https://github.com/Nanostring-Biostats/GeoDiff |
| Downloads rank | 260 |
| Source branch | RELEASE_3_23 |
| biocViews | DifferentialExpression, GeneExpression, Normalization, Software |
Documentation
Download
Dependencies
Depends: R (>= 4.1.0), Biobase
Imports: Matrix, robust, plyr, lme4, Rcpp (>= 1.0.4.6), withr, methods, graphics, stats, testthat, GeomxTools, NanoStringNCTools
LinkingTo: Rcpp, RcppArmadillo, roptim