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GSgalgoR

An Evolutionary Framework for the Identification and Study of Prognostic Gene Expression Signatures in Cancer

Bioconductor version: 3.23 · Package version: 1.22.0

A multi-objective optimization algorithm for disease sub-type discovery based on a non-dominated sorting genetic algorithm. The 'Galgo' framework combines the advantages of clustering algorithms for grouping heterogeneous 'omics' data and the searching properties of genetic algorithms for feature selection. The algorithm search for the optimal number of clusters determination considering the features that maximize the survival difference between sub-types while keeping cluster consistency high.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("GSgalgoR")

Details

MaintainerCarlos Catania <harpomaxx@gmail.com>
AuthorMartin Guerrero [aut], Carlos Catania [cre]
LicenseMIT + file LICENSE
URLhttps://github.com/harpomaxx/GSgalgoR
Bug Reportshttps://github.com/harpomaxx/GSgalgoR/issues
Downloads rank241
Source branchRELEASE_3_23
biocViewsClassification, Clustering, GeneExpression, Software, Survival, Transcription

Documentation

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Dependencies

Imports: cluster, doParallel, foreach, matchingR, nsga2R, survival, proxy, stats, methods

Suggests: knitr, rmarkdown, ggplot2, BiocStyle, genefu, survcomp, Biobase, survminer, breastCancerTRANSBIG, breastCancerUPP, iC10TrainingData, pamr, testthat