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GOaGO

Gene Ontology enrichment analysis of gene pairs

Bioconductor version: 3.23 · Package version: 1.0.1

GO-a-GO annotates Gene Ontology terms that are enriched in a given set of gene pairs. The enrichment is calculated from a permutation test for overrepresentation of gene pairs that are associated with a shared term. Such gene pairs are counted for the original set of gene pairs and compared against randomized sets in which the structure of the pairs is preserved, but the gene identities (including the associated terms) are permuted.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("GOaGO")

Details

MaintainerAleksander Jankowski <aleksander.jankowski@uw.edu.pl>
AuthorAleksander Jankowski [aut, cre] (ORCID: <https://orcid.org/0000-0002-2212-6224>)
LicenseArtistic-2.0
URLhttps://github.com/ajank/GOaGO
Bug Reportshttps://github.com/ajank/GOaGO/issues
Downloads rank50
Source branchRELEASE_3_23
biocViewsGO, GeneSetEnrichment, Software

Documentation

Download

Dependencies

Depends: R (>= 4.4.0), methods

Imports: AnnotationDbi, BiocGenerics, BiocParallel, clusterProfiler, data.table, DOSE, GenomeInfoDb, GenomicRanges, ggplot2, ggridges, Matrix, qvalue, S4Vectors

Suggests: BiocStyle, GenomicInteractions, ggrepel, knitr, org.Hs.eg.db, rmarkdown, rtracklayer, testthat, TxDb.Hsapiens.UCSC.hg19.knownGene