EpiDISH
Epigenetic Dissection of Intra-Sample-Heterogeneity
Bioconductor version: 3.23 · Package version: 2.28.0
EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of blood-tissue of any age, from birth to old-age, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("EpiDISH") Details
| Maintainer | Shijie C. Zheng <shijieczheng@gmail.com> |
| Author | Andrew E. Teschendorff [aut], Shijie C. Zheng [aut, cre] |
| License | GPL-2 |
| URL | https://github.com/sjczheng/EpiDISH |
| Bug Reports | https://github.com/sjczheng/EpiDISH/issues |
| Downloads rank | 1155 |
| Source branch | RELEASE_3_23 |
| biocViews | DNAMethylation, DifferentialMethylation, Epigenetics, ImmunoOncology, MethylationArray, Software |
Documentation
Download
Dependencies
Depends: R (>= 4.1)
Imports: MASS, e1071, quadprog, parallel, stats, matrixStats, stringr, locfdr, Matrix, genefilter
Suggests: roxygen2, GEOquery, BiocStyle, knitr, rmarkdown, Biobase, testthat
Reverse dependencies
Depends On Me (1): TOAST
Suggests Me (3): CimpleG, FlowSorted.Blood.EPIC, planet