Bioc2026 Registration Open!

EpiDISH

Epigenetic Dissection of Intra-Sample-Heterogeneity

Bioconductor version: 3.23 · Package version: 2.28.0

EpiDISH is a R package to infer the proportions of a priori known cell-types present in a sample representing a mixture of such cell-types. Right now, the package can be used on DNAm data of blood-tissue of any age, from birth to old-age, generic epithelial tissue and breast tissue. Besides, the package provides a function that allows the identification of differentially methylated cell-types and their directionality of change in Epigenome-Wide Association Studies.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("EpiDISH")

Details

MaintainerShijie C. Zheng <shijieczheng@gmail.com>
AuthorAndrew E. Teschendorff [aut], Shijie C. Zheng [aut, cre]
LicenseGPL-2
URLhttps://github.com/sjczheng/EpiDISH
Bug Reportshttps://github.com/sjczheng/EpiDISH/issues
Downloads rank1155
Source branchRELEASE_3_23
biocViewsDNAMethylation, DifferentialMethylation, Epigenetics, ImmunoOncology, MethylationArray, Software

Documentation

Download

Dependencies

Depends: R (>= 4.1)

Imports: MASS, e1071, quadprog, parallel, stats, matrixStats, stringr, locfdr, Matrix, genefilter

Suggests: roxygen2, GEOquery, BiocStyle, knitr, rmarkdown, Biobase, testthat

Reverse dependencies

Depends On Me (1): TOAST

Suggests Me (3): CimpleG, FlowSorted.Blood.EPIC, planet