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EasyCellType

Annotate cell types for scRNA-seq data

Bioconductor version: 3.23 · Package version: 1.14.0

We developed EasyCellType which can automatically examine the input marker lists obtained from existing software such as Seurat over the cell markerdatabases. Two quantification approaches to annotate cell types are provided: Gene set enrichment analysis (GSEA) and a modified versio of Fisher's exact test. The function presents annotation recommendations in graphical outcomes: bar plots for each cluster showing candidate cell types, as well as a dot plot summarizing the top 5 significant annotations for each cluster.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("EasyCellType")

Details

MaintainerRuoxing Li <ruoxingli@outlook.com>
AuthorRuoxing Li [aut, cre, ctb], Ziyi Li [ctb]
LicenseArtistic-2.0
Downloads rank241
Source branchRELEASE_3_23
biocViewsGeneExpression, GeneSetEnrichment, SingleCell, Software

Documentation

Download

Dependencies

Depends: R (>= 4.2.0)

Imports: clusterProfiler, dplyr, forcats, ggplot2, magrittr, rlang, stats, org.Hs.eg.db, org.Mm.eg.db, AnnotationDbi, vctrs (>= 0.6.4), BiocStyle

Suggests: knitr, rmarkdown, testthat (>= 3.0.0), Seurat, BiocManager, devtools, BiocStyle