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ELViS

An R Package for Estimating Copy Number Levels of Viral Genome Segments Using Base-Resolution Read Depth Profile

Bioconductor version: 3.23 · Package version: 1.4.0

Base-resolution copy number analysis of viral genome. Utilizes base-resolution read depth data over viral genome to find copy number segments with two-dimensional segmentation approach. Provides publish-ready figures, including histograms of read depths, coverage line plots over viral genome annotated with copy number change events and viral genes, and heatmaps showing multiple types of data with integrative clustering of samples.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ELViS")

Details

MaintainerJin-Young Lee <jlee307@uthsc.edu>
AuthorHyo Young Choi [aut, cph] (ORCID: <https://orcid.org/0000-0002-7627-8493>), Jin-Young Lee [aut, cre, cph] (ORCID: <https://orcid.org/0000-0002-5366-7488>), Xiaobei Zhao [ctb] (ORCID: <https://orcid.org/0000-0002-5277-0846>), Jeremiah R. Holt [ctb] (ORCID: <https://orcid.org/0000-0002-5201-5015>), Katherine A. Hoadley [aut] (ORCID: <https://orcid.org/0000-0002-1216-477X>), D. Neil Hayes [aut, fnd, cph] (ORCID: <https://orcid.org/0000-0001-6203-7771>)
LicenseMIT + file LICENSE
URLhttps://github.com/hyochoi/ELViS
Bug Reportshttps://github.com/hyochoi/ELViS/issues
Downloads rank165
Source branchRELEASE_3_23
biocViewsBiomedicalInformatics, Clustering, CopyNumberVariation, Coverage, GenomicVariation, Normalization, Sequencing, Software, Visualization

Documentation

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Dependencies

Depends: R (>= 4.5.0)

Imports: reticulate, BiocGenerics, circlize, ComplexHeatmap, data.table, dplyr, GenomicFeatures, GenomicRanges, ggplot2, glue, graphics, grDevices, igraph, IRanges, magrittr, memoise, methods, parallel, patchwork, scales, segclust2d, stats, stringr, txdbmaker, utils, uuid, zoo

Suggests: Rsamtools, BiocManager, knitr, testthat (>= 3.0.0)