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DominoEffect

Identification and Annotation of Protein Hotspot Residues

Bioconductor version: 3.23 · Package version: 1.32.0

The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("DominoEffect")

Details

MaintainerMarija Buljan <marija.buljan.2@gmail.com>, Peter Blattmann <peter_blattmann@bluewin.ch>
AuthorMarija Buljan and Peter Blattmann
LicenseGPL (>= 3)
Downloads rank292
Source branchRELEASE_3_23
biocViewsAlignment, Proteomics, SequenceMatching, Software, SomaticMutation

Documentation

Download

Dependencies

Depends: R (>= 3.5)

Imports: biomaRt, data.table, utils, stats, Biostrings, pwalign, SummarizedExperiment, VariantAnnotation, AnnotationDbi, Seqinfo, IRanges, GenomicRanges, methods

Suggests: knitr, testthat, rmarkdown