DegNorm
DegNorm: degradation normalization for RNA-seq data
Bioconductor version: 3.23 · Package version: 1.22.0
This package performs degradation normalization in bulk RNA-seq data to improve differential expression analysis accuracy. It provides estimates for each gene within each sample.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("DegNorm")Details
| Maintainer | Ji-Ping Wang <jzwang@northwestern.edu> |
| Author | Ji-Ping Wang [aut, cre] (ORCID: <https://orcid.org/0000-0002-8398-939X>) |
| License | LGPL (>= 3) |
| Bug Reports | https://github.com/jipingw/DegNorm/issues |
| Downloads rank | 295 |
| Source branch | RELEASE_3_23 |
| biocViews | Alignment, BatchEffect, Coverage, DataImport, DifferentialExpression, GeneExpression, ImmunoOncology, Normalization, QualityControl, RNASeq, Sequencing, Software |
Documentation
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Dependencies
Depends: R (>= 4.0.0), methods
Imports: Rcpp (>= 1.0.2), GenomicFeatures, txdbmaker, parallel, foreach, S4Vectors, doParallel, Rsamtools (>= 1.31.2), GenomicAlignments, heatmaply, data.table, stats, ggplot2, GenomicRanges, IRanges, plyr, plotly, utils, viridis
LinkingTo: Rcpp, RcppArmadillo, S4Vectors, IRanges