DegCre
Probabilistic association of DEGs to CREs from differential data
Bioconductor version: 3.23 · Package version: 1.8.0
DegCre generates associations between differentially expressed genes (DEGs) and cis-regulatory elements (CREs) based on non-parametric concordance between differential data. The user provides GRanges of DEG TSS and CRE regions with differential p-value and optionally log-fold changes and DegCre returns an annotated Hits object with associations and their calculated probabilities. Additionally, the package provides functionality for visualization and conversion to other formats.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("DegCre") Details
| Maintainer | Brian S. Roberts <brianroberts1976@yahoo.com> |
| Author | Brian S. Roberts [aut, cre] (ORCID: <https://orcid.org/0009-0001-2914-6826>) |
| License | MIT + file LICENSE |
| URL | https://github.com/brianSroberts/DegCre |
| Bug Reports | https://github.com/brianSroberts/DegCre/issues |
| Downloads rank | 203 |
| Source branch | RELEASE_3_23 |
| biocViews | ATACSeq, ChIPSeq, DNaseSeq, GeneExpression, GeneRegulation, RNASeq, Software |
Documentation
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Dependencies
Depends: R (>= 4.4)
Imports: GenomicRanges, InteractionSet, plotgardener, S4Vectors, stats, graphics, grDevices, BiocGenerics, Seqinfo, IRanges, BiocParallel, qvalue, TxDb.Hsapiens.UCSC.hg38.knownGene, org.Hs.eg.db, utils
Suggests: BSgenome, BSgenome.Hsapiens.UCSC.hg38, BiocStyle, magick, knitr, rmarkdown, TxDb.Mmusculus.UCSC.mm10.knownGene, testthat (>= 3.0.0)