DRIMSeq
Differential transcript usage and tuQTL analyses with Dirichlet-multinomial model in RNA-seq
Bioconductor version: 3.23 · Package version: 1.40.0
The package provides two frameworks. One for the differential transcript usage analysis between different conditions and one for the tuQTL analysis. Both are based on modeling the counts of genomic features (i.e., transcripts) with the Dirichlet-multinomial distribution. The package also makes available functions for visualization and exploration of the data and results.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("DRIMSeq")Details
| Maintainer | Malgorzata Nowicka <gosia.nowicka.uzh@gmail.com> |
| Author | Malgorzata Nowicka [aut, cre] |
| License | GPL (>= 3) |
| Downloads rank | 695 |
| Source branch | RELEASE_3_23 |
| biocViews | AlternativeSplicing, DifferentialExpression, DifferentialSplicing, GeneExpression, Genetics, ImmunoOncology, MultipleComparison, RNASeq, SNP, Sequencing, Software, WorkflowStep |
Documentation
Download
Dependencies
Depends: R (>= 3.4.0)
Imports: utils, stats, MASS, GenomicRanges, IRanges, S4Vectors, BiocGenerics, methods, BiocParallel, limma, edgeR, ggplot2, reshape2
Suggests: PasillaTranscriptExpr, GeuvadisTranscriptExpr, grid, BiocStyle, knitr, testthat