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CoSIA

An Investigation Across Different Species and Tissues

Bioconductor version: 3.23 · Package version: 1.12.1

Cross-Species Investigation and Analysis (CoSIA) is a package that provides researchers with an alternative methodology for comparing across species and tissues using normal wild-type RNA-Seq Gene Expression data from Bgee. Using RNA-Seq Gene Expression data, CoSIA provides multiple visualization tools to explore the transcriptome diversity and variation across genes, tissues, and species. CoSIA uses the Coefficient of Variation and Shannon Entropy and Specificity to calculate transcriptome diversity and variation. CoSIA also provides additional conversion tools and utilities to provide a streamlined methodology for cross-species comparison.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CoSIA")

Details

MaintainerAnthony B. Crumley <acrumley@uab.edu>
AuthorAnisha Haldar [aut] (ORCID: <https://orcid.org/0000-0002-1395-9793>), Vishal H. Oza [aut] (ORCID: <https://orcid.org/0000-0001-6990-0267>), Amanda D. Clark [aut] (ORCID: <https://orcid.org/0000-0002-1186-3114>), Anthony B. Crumley [cre, aut] (ORCID: <https://orcid.org/0009-0004-7347-4722>), Nathaniel S. DeVoss [aut] (ORCID: <https://orcid.org/0000-0003-0465-2770>), Brittany N. Lasseigne [aut] (ORCID: <https://orcid.org/0000-0002-1642-8904>)
LicenseMIT + file LICENSE
URLhttps://www.lasseigne.org/
Bug Reportshttps://github.com/lasseignelab/CoSIA/issues
Downloads rank201
Source branchRELEASE_3_23
biocViewsBiologicalQuestion, DataImport, GUI, GeneExpression, MultipleComparison, Software, ThirdPartyClient

Documentation

Download

Dependencies

Depends: R (>= 4.3.0), methods (>= 4.3.0), ExperimentHub (>= 2.7.0)

Imports: dplyr (>= 1.0.7), magrittr (>= 2.0.1), RColorBrewer (>= 1.1-2), tidyr (>= 1.2.0), plotly (>= 4.10.0), stringr (>= 1.4.0), ggplot2 (>= 3.3.5), tibble (>= 3.1.7), org.Hs.eg.db (>= 3.12.0), org.Mm.eg.db (>= 3.12.0), org.Dr.eg.db (>= 3.12.0), org.Ce.eg.db (>= 3.12.0), org.Dm.eg.db (>= 3.12.0), org.Rn.eg.db (>= 3.12.0), AnnotationDbi (>= 1.52.0), biomaRt (>= 2.46.3), homologene (>= 1.4.68.19), annotationTools (>= 1.64.0), readr (>= 2.1.1), tidyselect (>= 1.1.2), stats (>= 4.1.2)

Suggests: BiocStyle (>= 2.22.0), tidyverse (>= 1.3.1), knitr (>= 1.42), rmarkdown (>= 2.20), testthat (>= 3.1.6), qpdf (>= 1.3.0)