ChIPseeker
ChIPseeker for ChIP peak Annotation, Comparison, and Visualization
Bioconductor version: 3.23 · Package version: 1.48.0
This package implements functions to retrieve the nearest genes around the peak, annotate genomic region of the peak, statstical methods for estimate the significance of overlap among ChIP peak data sets, and incorporate GEO database for user to compare the own dataset with those deposited in database. The comparison can be used to infer cooperative regulation and thus can be used to generate hypotheses. Several visualization functions are implemented to summarize the coverage of the peak experiment, average profile and heatmap of peaks binding to TSS regions, genomic annotation, distance to TSS, and overlap of peaks or genes.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("ChIPseeker") Details
| Maintainer | Guangchuang Yu <guangchuangyu@gmail.com> |
| Author | Guangchuang Yu [aut, cre] (ORCID: <https://orcid.org/0000-0002-6485-8781>), Ming Li [ctb], Qianwen Wang [ctb], Yun Yan [ctb], Hervé Pagès [ctb], Michael Kluge [ctb], Thomas Schwarzl [ctb], Zhougeng Xu [ctb], Chun-Hui Gao [ctb] (ORCID: <https://orcid.org/0000-0002-1445-7939>) |
| License | Artistic-2.0 |
| URL | https://yulab-smu.top/contribution-knowledge-mining/ |
| Bug Reports | https://github.com/YuLab-SMU/ChIPseeker/issues |
| Downloads rank | 3046 |
| Source branch | RELEASE_3_23 |
| biocViews | Annotation, ChIPSeq, MultipleComparison, Software, Visualization |
Documentation
Download
Dependencies
Depends: R (>= 4.1.0)
Imports: AnnotationDbi, aplot, BiocGenerics, boot, dplyr, enrichplot, IRanges, GenomeInfoDb, GenomicRanges, GenomicFeatures, ggplot2, gplots, graphics, grDevices, gtools, magrittr, methods, plotrix, parallel, RColorBrewer, rlang, rtracklayer, S4Vectors, scales, stats, tibble, TxDb.Hsapiens.UCSC.hg19.knownGene, utils, yulab.utils (>= 0.2.0)
Suggests: clusterProfiler, ggimage, ggplotify, ggupset, ggVennDiagram, knitr, org.Hs.eg.db, prettydoc, ReactomePA, rmarkdown, testthat, TxDb.Hsapiens.UCSC.hg38.knownGene
Reverse dependencies
Imports Me (5): EpiCompare, epiRomics, esATAC, profileplyr, segmenter
Suggests Me (3): cinaR, curatedAdipoChIP, GRaNIE