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ChIPanalyser

ChIPanalyser: Predicting Transcription Factor Binding Sites

Bioconductor version: 3.23 · Package version: 1.34.0

ChIPanalyser is a package to predict and understand TF binding by utilizing a statistical thermodynamic model. The model incorporates 4 main factors thought to drive TF binding: Chromatin State, Binding energy, Number of bound molecules and a scaling factor modulating TF binding affinity. Taken together, ChIPanalyser produces ChIP-like profiles that closely mimic the patterns seens in real ChIP-seq data.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ChIPanalyser")

Details

MaintainerPatrick C.N. Martin <pcnmartin@gmail.com>
AuthorPatrick C.N.Martin & Nicolae Radu Zabet
LicenseGPL-3
Downloads rank354
Source branchRELEASE_3_23
biocViewsAlignment, BiologicalQuestion, ChIPSeq, ChipOnChip, Coverage, DataImport, PeakDetection, SequenceMatching, Sequencing, Software, Transcription, WorkflowStep

Documentation

Download

Dependencies

Depends: R (>= 3.5.0), GenomicRanges, Biostrings, BSgenome, RcppRoll, parallel

Imports: methods, IRanges, S4Vectors, grDevices, graphics, stats, utils, rtracklayer, ROCR, BiocManager, GenomeInfoDb, RColorBrewer

Suggests: BSgenome.Dmelanogaster.UCSC.dm6, knitr, RUnit, BiocGenerics