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Cepo

Cepo for the identification of differentially stable genes

Bioconductor version: 3.23 · Package version: 1.18.0

Defining the identity of a cell is fundamental to understand the heterogeneity of cells to various environmental signals and perturbations. We present Cepo, a new method to explore cell identities from single-cell RNA-sequencing data using differential stability as a new metric to define cell identity genes. Cepo computes cell-type specific gene statistics pertaining to differential stable gene expression.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Cepo")

Details

MaintainerHani Jieun Kim <hani.kim127@gmail.com>
AuthorHani Jieun Kim [aut, cre] (ORCID: <https://orcid.org/0000-0003-1844-3275>), Kevin Wang [aut] (ORCID: <https://orcid.org/0000-0003-2615-6102>)
LicenseMIT + file LICENSE
Downloads rank379
Source branchRELEASE_3_23
biocViewsClassification, DifferentialExpression, GeneExpression, Sequencing, SingleCell, Software

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Dependencies

Depends: GSEABase, R (>= 4.1)

Imports: DelayedMatrixStats, DelayedArray, HDF5Array, S4Vectors, methods, SingleCellExperiment, SummarizedExperiment, ggplot2, rlang, grDevices, patchwork, reshape2, BiocParallel, stats, dplyr, purrr

Suggests: knitr, rmarkdown, BiocStyle, testthat, covr, UpSetR, scater, scMerge, fgsea, escape, pheatmap

Reverse dependencies

Imports Me (1): scClassify