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CNVMetrics

Copy Number Variant Metrics

Bioconductor version: 3.23 · Package version: 1.16.0

The CNVMetrics package calculates similarity metrics to facilitate copy number variant comparison among samples and/or methods. Similarity metrics can be employed to compare CNV profiles of genetically unrelated samples as well as those with a common genetic background. Some metrics are based on the shared amplified/deleted regions while other metrics rely on the level of amplification/deletion. The data type used as input is a plain text file containing the genomic position of the copy number variations, as well as the status and/or the log2 ratio values. Finally, a visualization tool is provided to explore resulting metrics.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("CNVMetrics")

Details

MaintainerAstrid DeschĂȘnes <adeschen@hotmail.com>
AuthorAstrid DeschĂȘnes [aut, cre] (ORCID: <https://orcid.org/0000-0001-7846-6749>), Pascal Belleau [aut] (ORCID: <https://orcid.org/0000-0002-0802-1071>), David A. Tuveson [aut] (ORCID: <https://orcid.org/0000-0002-8017-2712>), Alexander Krasnitz [aut]
LicenseArtistic-2.0
URLhttps://github.com/krasnitzlab/CNVMetrics, https://krasnitzlab.github.io/CNVMetrics/
Bug Reportshttps://github.com/krasnitzlab/CNVMetrics/issues
Downloads rank241
Source branchRELEASE_3_23
biocViewsBiologicalQuestion, CopyNumberVariation, Software

Documentation

Download

Dependencies

Depends: R (>= 4.0)

Imports: GenomicRanges, IRanges, S4Vectors, BiocParallel, methods, magrittr, stats, pheatmap, gridExtra, grDevices, rBeta2009

Suggests: BiocStyle, knitr, rmarkdown, testthat, XVector