CAGEfightR
Analysis of Cap Analysis of Gene Expression (CAGE) data using Bioconductor
Bioconductor version: 3.23 · Package version: 1.32.0
CAGE is a widely used high throughput assay for measuring transcription start site (TSS) activity. CAGEfightR is an R/Bioconductor package for performing a wide range of common data analysis tasks for CAGE and 5'-end data in general. Core functionality includes: import of CAGE TSSs (CTSSs), tag (or unidirectional) clustering for TSS identification, bidirectional clustering for enhancer identification, annotation with transcript and gene models, correlation of TSS and enhancer expression, calculation of TSS shapes, quantification of CAGE expression as expression matrices and genome brower visualization.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("CAGEfightR") Details
| Maintainer | Malte Thodberg <maltethodberg@gmail.com> |
| Author | Malte Thodberg |
| License | GPL-3 + file LICENSE |
| URL | https://github.com/MalteThodberg/CAGEfightR |
| Bug Reports | https://github.com/MalteThodberg/CAGEfightR/issues |
| Downloads rank | 489 |
| Source branch | RELEASE_3_23 |
| biocViews | Annotation, Coverage, DataImport, DataRepresentation, GeneExpression, GeneRegulation, GenomeBrowsers, Normalization, PeakDetection, Preprocessing, Sequencing, Software, Transcription, Transcriptomics, Visualization |
Documentation
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Dependencies
Depends: R (>= 3.5), GenomicRanges (>= 1.61.1), rtracklayer (>= 1.69.1), SummarizedExperiment (>= 1.39.1)
Imports: lobstr (>= 1.1.3), purrr (>= 1.2.0), assertthat (>= 0.2.0), methods (>= 3.6.3), Matrix (>= 1.2-12), BiocGenerics (>= 0.24.0), S4Vectors (>= 0.16.0), IRanges (>= 2.12.0), Seqinfo (>= 1.0.0), GenomicFeatures (>= 1.61.4), GenomicAlignments (>= 1.45.1), BiocParallel (>= 1.12.0), GenomicFiles (>= 1.14.0), Gviz (>= 1.22.2), InteractionSet (>= 1.9.4), GenomicInteractions (>= 1.15.1)
Suggests: knitr, rmarkdown, BiocStyle, org.Mm.eg.db, TxDb.Mmusculus.UCSC.mm9.knownGene
Reverse dependencies
Depends On Me (1): CAGEWorkflow
Imports Me (1): CAGEr
Suggests Me (1): nanotubes