BulkSignalR
Infer Ligand-Receptor Interactions from bulk expression (transcriptomics/proteomics) data, or spatial transcriptomics
Bioconductor version: 3.23 · Package version: 1.4.0
Inference of ligand-receptor (LR) interactions from bulk expression (transcriptomics/proteomics) data, or spatial transcriptomics. BulkSignalR bases its inferences on the LRdb database included in our other package, SingleCellSignalR available from Bioconductor. It relies on a statistical model that is specific to bulk data sets. Different visualization and data summary functions are proposed to help navigating prediction results.
Installation
if (!require("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("BulkSignalR") Details
| Maintainer | Jean-Philippe Villemin <jpvillemin@gmail.com> |
| Author | Jacques Colinge [aut] (ORCID: <https://orcid.org/0000-0003-2466-4824>), Jean-Philippe Villemin [cre] (ORCID: <https://orcid.org/0000-0002-1838-5880>) |
| License | CeCILL | file LICENSE |
| URL | https://github.com/jcolinge/BulkSignalR |
| Bug Reports | https://github.com/jcolinge/BulkSignalR/issues |
| Downloads rank | 281 |
| Source branch | RELEASE_3_23 |
| biocViews | Network, NetworkInference, Proteomics, RNASeq, Software, Spatial, Transcriptomics |
Documentation
- BulkSignalR : Inference of ligand-receptor interactions from bulk data or spatial transcriptomics
- BulkSignalR : Inference of ligand-receptor interactions from bulk data or spatial transcriptomics
- BulkSignalR : Inference of ligand-receptor interactions from bulk data or spatial transcriptomics
Download
Dependencies
Depends: R (>= 4.5)
Imports: BiocFileCache, httr2, RCurl, cli, curl, rlang, jsonlite, matrixStats, methods, doParallel, glmnet, ggalluvial, ggplot2, gridExtra, grid, Rtsne, ggrepel, foreach, multtest, igraph, orthogene, stabledist, circlize (>= 0.4.14), ComplexHeatmap (>= 2.0.0), stats, scales, RANN, SpatialExperiment, SummarizedExperiment, tools
Suggests: knitr, markdown, rmarkdown, STexampleData, testthat (>= 3.0.0), codetools, Matrix, lattice, cluster, survival, MASS, nlme
Reverse dependencies
Imports Me (1): SingleCellSignalR