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BioPlex

R-side access to BioPlex protein-protein interaction data

Bioconductor version: 3.23 · Package version: 1.18.0

The BioPlex package implements access to the BioPlex protein-protein interaction networks and related resources from within R. Besides protein-protein interaction networks for HEK293 and HCT116 cells, this includes access to CORUM protein complex data, and transcriptome and proteome data for the two cell lines. Functionality focuses on importing the various data resources and storing them in dedicated Bioconductor data structures, as a foundation for integrative downstream analysis of the data.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("BioPlex")

Details

MaintainerLudwig Geistlinger <ludwig_geistlinger@hms.harvard.edu>
AuthorLudwig Geistlinger [aut, cre], Robert Gentleman [aut]
LicenseArtistic-2.0
URLhttps://github.com/ccb-hms/BioPlex
Bug Reportshttps://github.com/ccb-hms/BioPlex/issues
Downloads rank101
Source branchRELEASE_3_23
biocViewsCellCulture, ColonCancerData, ExperimentData, ExperimentHub, ExpressionData, GEO, Genome, Homo_sapiens_Data, MassSpectrometryData, Proteome, RNASeqData, ReproducibleResearch

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Dependencies

Depends: R (>= 4.1.0), SummarizedExperiment

Imports: BiocFileCache, GEOquery, graph, methods, utils

Suggests: AnnotationDbi, AnnotationHub, BiocStyle, DEXSeq, ExperimentHub, depmap, knitr, rmarkdown