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AffiXcan

A Functional Approach To Impute Genetically Regulated Expression

Bioconductor version: 3.23 · Package version: 1.30.0

Impute a GReX (Genetically Regulated Expression) for a set of genes in a sample of individuals, using a method based on the Total Binding Affinity (TBA). Statistical models to impute GReX can be trained with a training dataset where the real total expression values are known.

Installation

if (!require("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("AffiXcan")

Details

MaintainerAlessandro Lussana <alessandro.lussana@protonmail.com>
AuthorAlessandro Lussana [aut, cre]
LicenseGPL-3
Downloads rank287
Source branchRELEASE_3_23
biocViewsDimensionReduction, GeneExpression, GeneRegulation, PrincipalComponent, Regression, Software, Transcription

Documentation

Download

Dependencies

Depends: R (>= 3.6), SummarizedExperiment

Imports: MultiAssayExperiment, BiocParallel, crayon

Suggests: BiocStyle, knitr, rmarkdown