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Domain combination graph

alpha-helical ferredoxin Nucleotide-binding domain GreA transcript cleavage protein, N-terminal domain FKBP-like Chaperone J-domain HSP40/DnaJ peptide-binding domain Effector domain of the protein kinase pkn/prk1 A class II aminoacyl-tRNA synthetase N-domain Class II aaRS and biotin synthetases C-terminal UvrC-binding domain of UvrB Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain Cytochrome c Homeodomain-like Ribonuclease H-like Methylated DNA-protein cysteine methyltransferase, C-terminal domain Iron-dependent represor protein, dimerization domain Phosphosugar isomerase Actin-like ATPase domain S-adenosyl-L-methionine-dependent methyltransferases PLP-dependent transferases Periplasmic binding protein-like II C-terminal domain of arginine repressor GAF domain-like Lrp/AsnC-like transcriptional regulator C-terminal domain C-terminal effector domain of the bipartite response regulators Ribosomal protein L11, C-terminal domain Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 Ribosomal protein S5 domain 2-like DNA helicase RuvA subunit, C-terminal domain UBA-like Elongation factor Ts (EF-Ts), dimerisation domain N-terminal domain of phosphatidylinositol transfer protein sec14p C-terminal domain of phosphatidylinositol transfer protein sec14p Putative DNA-binding domain Spectrin repeat Succinate dehydrogenase/fumarate reductase C-terminal domain Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases Second domain of FERM PH domain-like PGBD-like Metalloproteases ( HMG-box Acyl-CoA dehydrogenase (flavoprotein), C-terminal domain alpha-catenin/vinculin Histidine-containing phosphotransfer domain, HPT domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases ACP-like Domain of the SRP/SRP receptor G-proteins P-loop containing nucleotide triphosphate hydrolases Bromodomain Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase lambda repressor-like DNA-binding domains RmlC-like cupins Periplasmic binding protein-like I Signal peptide-binding domain Helix-loop-helix DNA-binding domain PYP-like sensor domain EF-hand Phosphatidylinositol-specific phospholipase C (PI-PLC) Calponin-homology domain, CH-domain Glutathione S-transferases, C-terminal domain Methionine synthase domain Cobalamin (vitamin B12)-binding domain Pyrimidine nucleoside phosphorylase N-terminal domain Pyrimidine nucleoside phosphorylase central domain STAT p53-like transcription factors Transferrin receptor ectodomain, C-terminal domain CO dehydrogenase ISP C-domain like FAD-binding domain Chemotaxis receptor methyltransferase CheR, N-terminal domain SAM/Pointed domain RuvA domain 2-like BRCT domain C-terminal domain of RNA polymerase alpha subunit 5' to 3' exonuclease, C-terminal subdomain lambda integrase-like, N-terminal domain DNA breaking-rejoining enzymes Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain Saposin C-terminal domain of alpha and beta subunits of F1 ATP synthase Ypt/Rab-GAP domain of gyp1p Cyclin-like DNA polymerase III clamp loader subunits, C-terminal domain Guanido kinases Glutamine synthase/guanidino kinase catalytic domain DBL homology domain (DH-domain) Regulator of G-protein signalling, RGS Protein kinase-like (PK-like) Carbamoyl phosphate synthetase, large subunit connection domain Biotin carboxylase N-terminal domain-like DNA-glycosylase An anticodon-binding domain of class I aminoacyl-tRNA synthetases R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes FAD-binding (C-terminal) domain of DNA photolyase 6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose dehydrogenase (UDPGDH), C-terminal (UDP-binding) domain Terpenoid cylases/Protein prenyltransferases Terpenoid synthases FIS-like Ribosomal protein L7/12, oligomerisation (N-terminal) domain Ribosomal protein L7/12, C-terminal domain Aldehyde ferredoxin oxidoreductase, C-terminal domains DNA repair protein MutS, domain III Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain GTPase activation domain, GAP ARM repeat Ankyrin repeat Sec7 domain TPR-like Lipoxigenase Skp1-Skp2 dimerisation domains RNI-like Nuclear receptor ligand-binding domain Immunoglobulin Fibronectin type III (Trans)glycosidases Cysteine proteinases PKD domain beta-Galactosidase/glucuronidase domain Transglutaminase, two C-terminal domains Cadherin PapD-like Periplasmic chaperone C-domain Purple acid phosphatase, N-terminal domain Metallo-dependent phosphatases Invasin/intimin cell-adhesion fragments SH2 domain Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor Carboxypeptidase D, a regulatory domain Cupredoxins C2 domain (Calcium/lipid-binding domain, CaLB) TRAF domain-like POZ domain Lipase/lipooxygenase domain (PLAT/LH2 domain) PHM/PNGase F Calpain large subunit, middle domain (domain III) Galactose-binding domain-like Spermadhesin, CUB domain EGF/Laminin LDL receptor-like module Complement control module/SCR domain Concanavalin A-like lectins/glucanases C-terminal domain of transcriptional repressors SH3-domain Translation proteins SH3-like domain GroES-like NAD(P)-binding Rossmann-fold domains PDZ domain-like Staphylococcal nuclease Nucleic acid-binding proteins Prokaryotic type KH domain (pKH-domain) B3/B4 domain of PheRS, PheT MOP-like CheW-like CheY-like Ricin B-like lectins Actin-crosslinking proteins Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain Initiation factor IF2/eIF5b, domain 3 Elongation factor G (EF-G), domains III and V FMT C-terminal domain-like Trypsin-like serine proteases N-terminal domain of alpha and beta subunits of F1 ATP synthase Alanine racemase-like, C-terminal domain Acid proteases ADC-like Cdc48 domain 2-like Ribosomal protein L25-like Cysteine-rich domain PK beta-barrel domain-like Nucleotidylyl transferase Mannose 6-phosphate receptor domain Hemopexin-like domain Prolyl oligopeptidase, N-terminal domain alpha/beta-Hydrolases alpha-Amylases, C-terminal beta-sheet domain WW domain Vitelline membrane outer protein-I (VMO-I) Mannose-binding lectins Trimeric LpxA-like enzymes cAMP-binding domain-like Single hybrid motif Rudiment single hybrid motif FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain PLP-binding barrel Beta-D-glucan exohydrolase, C-terminal domain Enolase C-terminal domain-like Phosphoenolpyruvate/pyruvate domain Pyruvate kinase, C-terminal domain Quinolinic acid phosphoribosyltransferase, C-terminal domain Dihydropteroate synthetase-like Succinyl-CoA synthetase domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain Lactate & malate dehydrogenases, C-terminal domain Glutamyl tRNA-reductase dimerization domain FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase MurD, N-terminal domain MurD-like peptide ligases, catalytic domain Aconitase Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like L domain-like Growth factor receptor domain ClpP/crotonase Flavoproteins Riboflavin synthase domain-like Formate/glycerate dehydrogenase catalytic domain-like Methylglyoxal synthase-like AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC Ferredoxin reductase-like, C-terminal NADP-linked domain Alpha-L RNA-binding motif Adenine nucleotide alpha hydrolases GMP synthetase C-terminal dimerisation domain Argininosuccinate synthetase, C-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain N-terminal domain of DNA photolyase ETFP adenine nucleotide-binding domain-like DHS-like NAD/FAD-binding domain Glutathione synthetase ATP-binding domain-like Thiamin diphosphate-binding fold (THDP-binding) Tubulin, GTPase domain Tubulin, C-terminal domain D-ribose-5-phosphate isomerase (RpiA), lid domain Transketolase C-terminal domain-like Phosphoglycerate mutase-like RecA protein, C-terminal domain Subtilisin-like Firefly luciferase-like (Phosphotyrosine protein) phosphatases II Rhodanese/Cell cycle control phosphatase Thioredoxin-like Leucine aminopeptidase (Aminopeptidase A), N-terminal domain Zn-dependent exopeptidases Anticodon-binding domain of Class II aaRS C-terminal domain of ProRS Resolvase-like Heat shock protein 70kD (HSP70), C-terminal substrate-binding fragment Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase DNA/RNA polymerases Translational machinery components L30e-like DNA repair protein MutS, domain II Methylated DNA-protein cysteine methyltransferase domain Molybdenum cofactor biosynthesis proteins Molybdenum cofactor biosynthesis protein MoeA, C-terminal domain Aminoacid dehydrogenase-like, N-terminal domain MurD-like peptide ligases, peptide-binding domain PRTase-like Integrin A (or I) domain Integrin domains CoA transferase Formyltransferase Nucleotide-diphospho-sugar transferases Ribokinase-like Carbamate kinase-like Archaeosine tRNA-guanine transglycosylase, C-terminal additional domains Aspartate/ornithine carbamoyltransferase Aspartate/glutamate racemase Tryptophan synthase beta subunit-like PLP-dependent enzymes Regulatory domain in the aminoacid metabolism SIS domain Formate dehydrogenase/DMSO reductase, domains 1-3 Aconitase iron-sulfur domain Phosphoglucomutase, first 3 domains PEP carboxykinase-like Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain Thiolase-like LysM domain Chromo domain-like GHMP Kinase Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5 Type II DNA topoisomerase Ubiquitin-like 2Fe-2S ferredoxin-like Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain Glutamine synthetase, N-terminal domain MHC antigen-recognition domain Diaminopimelate epimerase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CBS-domain Thioesterase/thiol ester dehydrase-isomerase CO dehydrogenase molybdoprotein N-domain-like Molybdemum cofactor-binding domain Quinolinic acid phosphoribosyltransferase, N-terminal domain Ribosomal protein L11, N-terminal domain dsRNA-binding domain-like Eukaryotic type KH-domain (eKH-domain) Ribosomal protein S3 C-terminal domain Enolase N-terminal domain-like 4Fe-4S ferredoxins Protease propeptides/inhibitors RNA-binding domain, RBD Anticodon-binding domain of PheRS Metal-binding domain Adenylyl and guanylyl cyclase catalytic domain FAD-linked oxidases, C-terminal domain Pseudouridine synthase Sulfite reductase, domains 1 and 3 Sulfite reductase hemoprotein (SiRHP), domains 2 and 4 Threonyl-tRNA synthetase (ThrRS), second <code>additional</code> domain Arginyl-tRNA synthetase (ArgRS), N-terminal <code>additional</code> domain RBP11-like subunits of RNA polymerase DNA repair protein MutS, domain I alpha/beta knot Aminoimidazole ribonucleotide synthetase (PurM) N-terminal domain Aminoimidazole ribonucleotide synthetase (PurM) C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain CO dehydrogenase flavoprotein C-terminal domain-like N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 Blood coagulation inhibitor (disintegrin) beta-N-acetylhexosaminidase domain Ribosomal protein L9 C-domain L9 N-domain-like Acyl-CoA N-acyltransferases (Nat) Actin depolymerizing proteins 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain TATA-box binding protein-like S-adenosylmethionine synthetase DNA clamp Phospholipase D/nuclease Ribosomal protein L6 DNA ligase/mRNA capping enzyme, catalytic domain Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 4'-phosphopantetheinyl transferase Aldehyde ferredoxin oxidoreductase, N-terminal domain N-terminal nucleophile aminohydrolases (Ntn hydrolases) Metallo-hydrolase/oxidoreductase C-type lectin-like Scavenger receptor cysteine-rich (SRCR) domain Penicillin-binding protein 2x (pbp-2x), N-terminal domain beta-Lactamase/D-ala carboxypeptidase Penicillin-binding protein 5, C-terminal domain Acyl-CoA dehydrogenase (flavoprotein), N-terminal and middle domains DNA primase DnaG catalytic core Membrane all-alpha TB module/8-cys domain Low density lipoprotein (LDL) reseptor YWTD domain Integrin beta tail domain BPTI-like Hairpin loop containing domain-like Kringle-like Ovomucoid/PCI-1 like inhibitors Serine proterase inhibitors TNF receptor-like Fibronectin type I module Tachycitin C2H2 and C2HC zinc fingers FYVE/PHD zinc finger Glucocorticoid receptor-like (DNA-binding domain) Retrovirus zinc finger-like domains Zinc beta-ribbon B-box zinc-binding domain RING finger domain, C3HC4 LuxS/MPP-like metallohydrolase MurE/MurF N-terminal domain PTS-regulatory domain, PRD Leukotriene A4 hydrolase N-terminal domain Molybdenum cofactor biosynthesis protein MoeA, N-terminal and linker domains YjeF N-terminal domain-like PEP carboxykinase N-terminal domain RNase III endonuclease domain Integrin alpha N-terminal domain Transcription factor NusA, N-terminal domain Glutamyl tRNA-reductase catalytic, N-terminal domain Serine proteinase inhibitor lekti, domain one Culin repeat Culin homology domain YhbC-like, C-terminal domain YhbC-like, N-terminal domain Pheromone-binding domain of LuxR-like quorum-sensing transcription factors Clathrin coat assembly domain Zinc-binding domain of translation initiation factor 2 beta

Wolfgang Huber
Last modified: Mon Jul 21 13:40:25 MEST 2003